Colleen Deane

Colleen Deane

  • cdeane at bournemouth dot ac dot uk
Back to top

Biography

I have joined the School of Health and Social Care to commence a BU matched funded PhD studentship investigating novel mechanisms regulating muscle mass in the elderly. I have just successfully completed my Masters (with distinction) in Physical Activity, Nutrition and Health Promotion, where I investigated the effects of specific hormones (Testosterone) and polyphenols (Resveratrol) on artificially aged skeletal muscle cells, extracted from mice. My PhD aims to enhance current understanding of the mechanisms regulating age-related loss of skeletal muscle mass (termed ‘sarcopenia’) and the associated reductions in mobility, general health and quality of life. Whilst exercise and nutritional interventions improve muscle size and function in young individuals, this response is attenuated in elderly muscle. Thus, using a combination of physiological and metabolic/molecular techniques these studies will investigate novel mechanisms underlying the blunted response of ageing muscle to exercise and nutritional growth stimuli.

Journal Articles

  • Deane, C.S., Wilkinson, D.J., Phillips, B.E., Smith, K., Etheridge, T., Atherton, P.J., 2017. “Nutraceuticals” in relation to human skeletal muscle and exercise. American Journal of Physiology Endocrinology and Metabolism, 312 (4), E282-E299.
  • Sharples, A.P., Hughes, D.C., Deane, C.S., Saini, A., Selman, C., Stewart, C.E., 2015. Longevity and skeletal muscle mass: The role of IGF signalling, the sirtuins, dietary restriction and protein intake. Aging Cell, 14 (4), 511-523.
  • Deane, C.S., Hughes, D.C., Sculthorpe, N., Lewis, M.P., Stewart, C.E., Sharples, A.P., 2013. Impaired hypertrophy in myoblasts is improved with testosterone administration. The Journal of Steroid Biochemistry and Molecular Biology, 138.
  • Bailey, D., Fairclough, S., Savory, L., Denton, S., Pang, D., Deane, C., Kerr, C.. Accelerometry-assessed sedentary behaviour and physical activity levels during the segmented school day in 10-14-year-old children: the HAPPY study. European Journal of Pediatrics, Epub ahead of print (Epub ahead of print).

Conferences

  • Deane, C., Hughes, D., Sculthorpe, N., Sharples, A.. Testosterone rescues differentiation and hypertrophy in artificially aged skeletal muscle myoblasts. In: International Conference of Strength Training 24/10/2012 Oslo, Norway.

Theses

  • Deane, C.. Exploring metabolic and molecular mechanisms regulating age-related declines in human skeletal muscle regenerative capacity. Bournemouth University, Faculty of Health and Social Sciences.

Grants

  • Investigating novel metabolic / molecular mechanisms regulating age-related loss and repair of muscle mass and function (Santander, 01 May 2013). Awarded

Qualifications

  • MSc in Physical Activity, Nutrition and Health Promotion (2012)
  • BSc (Hons) in Sport and Exercise Science (2011)

Memberships

The data on this page was last updated at 05:00 on February 18, 2026.